USB 3.0 drives are generally faster, though they will run at USB 2.0 speeds on the 360.
For backup copies or homebrew – requires RGH/JTAG modded console. install games xbox 360 usb best
Scratched discs often become unreadable during intense seek operations. Installing from a slightly scratched disc works once; thereafter, the console reads from USB, sparing the disc further damage. USB 3.0 drives are generally faster