systems (including the New 2DS XL) due to the higher processing power required; it will not run on original 3DS or 2DS hardware.
Because the Nintendo 3DS eShop officially closed its doors in March 2023, purchasing the game digitally through official channels is no longer possible. This has turned the community toward ROM emulation and digital archiving to experience the game. Understanding 3DS ROM Formats: .3DS vs. .CIA isaac 3ds rom
Exploring The Binding of Isaac: Rebirth on 3DS: ROMs, ROM Hacks, and Console Performance systems (including the New 2DS XL) due to
❌ Original Nintendo 3DS, 3DS XL, or Nintendo 2DS. or Nintendo 2DS.