A "Portable" version is not an official product created or sanctioned by Adobe. Instead, it is created by third-party crackers or enthusiasts using virtualization software (such as VMware ThinApp or Cameyo). These tools package the core executables, registries, and dependencies of the software into a single, self-contained executable file ( .exe ).
Adobe InDesign CS6 Portable is an unauthorized, repackaged version of Adobe’s 2012 desktop publishing software (CS6) designed to run from a USB drive or external disk without installation. It targets users who need page layout capabilities on shared or restricted computers. Adobe InDesign CS6 Portable